About Us

The Transplant Laboratory

Our transplant laboratory is a fully accredited “state of the art” facility performing histocompatibility testing of organ donors and recipients. The laboratory also plays a critical role in the pre and post-transplant evaluation, and successful transplantation of highly sensitized individuals who would be difficult to treat under general conditions. The laboratory has been recognized by National agencies for pioneering the testing, and for facilitating the successful transplantation of these difficult to match individuals. For its efforts, the NJ Sharing Network Transplant Laboratory has been awarded National Kidney registry (NKR) awards in 2011 and 2014. 

 

The Laboratory is directed by Prakash Rao, PhD, MBA, FACHE, HCLD.  Dr. Rao is a board certified High Complexity Clinical Laboratory Director with certifications in histocompatibility and cancer testing.  Dr. Rao is a Fellow of the American College of Healthcare Executives. 

 

The Laboratory is maintained by a highly trained and motivated personnel certified by several different agencies including ASCP, ABHI and New York State.  The laboratory is staffed 24/7 and performs routine as well as STAT testing on potential organ donors and recipients. 

 

Testing includes HLA typing, HLA antibody screen and identification, crossmatches by complement dependent cytotoxicity and Flow Cytometry, ABO type and screen, ABO Rh and ABO titers.  These procedures form the basis of compatibility determination between potential organ donors and recipients.  In the post-transplant period, the laboratory provides the clinician with tools to monitor and predict impending clinical rejection and graft failure.  

 

The Laboratory provides these services to Newark Beth Israel Medical Center for Heart and Lung transplant, Saint Barnabas Medical Center for Renal/Pancreas transplant, Robert Wood Johnson for Heart and Renal/Pancreas transplant, Hackensack for Renal/Pancreas transplant, UMDNJ for Liver transplant, Our Lady of Lourdes Renal/Pancreas transplant and Rutgers Cancer Institute of New Jersey for Bone Marrow testing.  The laboratory therefore serves as a very valuable resource for transplant center physicians and provides them with the tools to streamline their therapeutic efforts.  More recently, the laboratory was part of transplant history, being involved in carrying out the compatibility testing for the 6 way kidney swap with several of our transplant centers. In addition to its clinical service duties, the laboratory also serves as a valuable training resource for clinical residents and fellows in training from client transplant institutions, and for students of the Clinical Laboratory Sciences program of Rutgers University. Cutting edge transplantation research carried out in the laboratory is directed towards identifying markers of donor organ viability and function, personalized transplantation medicine, and regenerative medicine.

 

The laboratory continues to play a key role in completing the Circle of Life. To date, the lab is credited with saving the lives of over 8,000 New Jersey residents.

 

Testing

  • Immunohematology - hemagglutination method
    ABO/Rh type, A subgrouping
    RBC antibody screening and identification
    ABO antibody titer (isoagglutinin titer)
  • Histocompatibility testing HLA-A B C DR DQ DQA DP typing by rSSOP and SSP
    HLA antibody screening class I and class II by flow cytometry, and identification by Luminex technology
    Crossmatch, T and B cells by CDC and flow cytometry

 

Guidelines

Please refer to the following guidelines for submissions:

Requirements and Instructions for Monthly Specimens

Please use the form below to request canisters:

Request for Canisters

Please use the following forms when submitting tests and/or specimens: 

Request for Pre-Transplant Studies

Request for Pre-Transplant Studies for Paired Exchange Program 

HLA Antibody Test Request Form

Bone Marrow Test Request Form


FOR QUESTIONS OR SUPPLIES CALL
(908) 516-5454

Lab staff

 

Laboratory-at-TSN